Oncology & Cancer

Lycopene inversely linked to renal cell carcinoma risk

(HealthDay)—For postmenopausal women, lycopene intake seems to be inversely associated with the risk of renal cell carcinoma (RCC), according to a study published in the Feb. 15 issue of Cancer.

Oncology & Cancer

How a common antacid could lead to cheaper anti-cancer drugs

A popular indigestion medication can increase survival in colorectal cancer, according to research published in ecancermedicalscience. But in fact, scientists have studied this for years - and a group of cancer advocates ...

Medical research

New hope for kidney cancer treatment using existing drugs

The most comprehensive study of kidney cancer at single-cell level has discovered a potential drug target to treat renal cell carcinoma, a cancer with a high mortality rate that is hard to detect. Researchers from the Wellcome ...

Oncology & Cancer

Research shows surgery adds years for kidney cancer patients

Mayo Clinic researchers have discovered that surgery could more than double life expectancy for many patients with late-stage kidney cancer, giving them anywhere from two to almost 10 years more than they'd have without the ...

Genetics

Single-cell sequencing leads to a new era of cancer research

BGI, the world's largest genomics organization, developed single-cell genome sequencing technology and published two research papers for cancer single-cell sequencing in the research journal Cell. In the papers, which were ...

Diabetes

Diabetes predicts worse survival in renal cell carcinoma

(HealthDay)—Diabetes mellitus is associated with worse prognosis in terms of progression-free, overall, and cancer-specific survival in patients with renal cell carcinoma treated surgically, according to a study published ...

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Renal cell carcinoma (RCC, also known as hypernephroma) is a kidney cancer that originates in the lining of the proximal convoluted tubule, the very small tubes in the kidney that filter the blood and remove waste products. RCC is the most common type of kidney cancer in adults, responsible for approximately 80% of cases. It is also known to be the most lethal of all the genitourinary tumors.[citation needed] Initial treatment is most commonly a radical or partial nephrectomy and remains the mainstay of curative treatment. Where the tumor is confined to the renal parenchyma, the 5-year survival rate is 60-70%, but this is lowered considerably where metastases have spread. It is relatively resistant to radiation therapy and chemotherapy, although some cases respond to immunotherapy. Targeted cancer therapies such as sunitinib, temsirolimus, bevacizumab, interferon-alpha, and sorafenib have improved the outlook for RCC (progression-free survival), although they have not yet demonstrated improved survival.

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