FDA approves Tremfya for ulcerative colitis
The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.
Sep 17, 2024
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Global trial ends 20-year debate over gastro-esophageal cancer treatment
Cancer patients could avoid unnecessary radiation therapy as a result of an international clinical trial, led by Peter Mac researcher Prof Trevor Leong. The TOPGEAR study demonstrated that radiotherapy does not improve survival ...
Sep 16, 2024
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High-dose vitamin D3 does not provide benefit for metastatic colorectal cancer, clinical trial shows
SOLARIS (Alliance A021703), a multicenter, double-blind, randomized Phase III clinical trial led by Dana-Farber Cancer Institute researchers and conducted across several hundred cancer centers in the U.S. tested the addition ...
Sep 16, 2024
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New insight into the effects of proton-pump inhibitors in children
Proton-pump inhibitors (PPIs) are frequently prescribed to suppress stomach acid in patients with gastroesophageal reflux disease (GERD). Prescribing rates of PPIs in children have risen more than 500% in the past two decades, ...
Sep 16, 2024
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Cellular map of the pancreas could lead to better treatments against pancreatic cancer and diabetes
Pancreatic diseases, such as diabetes or pancreatic cancer, are usually severe and have a strong impact on patients. Unfortunately, today, there are no specific or effective treatments for pancreatic cancer, so the survival ...
Sep 13, 2024
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Gut reaction: Low levels of manganese can aggravate inflammatory bowel disease
Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of the micronutrient can exacerbate intestinal injury ...
Sep 12, 2024
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Gut microbiome found to influence location of immune cells
Researchers at the Experimental and Clinical Research Center of Max Delbrück Center and Charité—Universitätsmedizin Berlin (ECRC) have found that different anatomical sections of the gastrointestinal tracts of mice carry ...
Sep 12, 2024
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Which gut drugs might end up in a lawsuit? Are there really links with cancer and kidney disease?
Common medicines used to treat conditions including heartburn, reflux, indigestion and stomach ulcers may be the subject of a class action lawsuit in Australia.
Sep 12, 2024
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Research extends hope for gastric cancer patients with peritoneal metastasis
Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with more than 1,000,000 new cases and close to 770,000 deaths each year. ...
Sep 12, 2024
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Study reveals how antibiotics contribute to inflammatory bowel disease risk
In a study published in Science Advances, Dr. Shai Bel and his research team at the Azrieli Faculty of Medicine of Bar-Ilan University have uncovered crucial insights into how antibiotic use increases the risk of inflammatory ...
Sep 11, 2024
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Thanks to Reddit, a new diagnosis is bubbling up across the nation
In a video posted to Reddit this summer, Lucie Rosenthal's face starts focused and uncertain, looking intently into the camera, before it happens.
Sep 11, 2024
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'It's okay to poo at work': New health campaign highlights a common source of anxiety
For most people, the daily or near-daily ritual of having a bowel movement is not something we give a great deal of thought to. But for some people, the need to do a "number two" in a public toilet or at work can be beset ...
Sep 11, 2024
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A GPS for the gastrointestinal system
Two Texas Tech Health El Paso gastroenterology researchers are receiving recognition for their clinical investigation of an electronic capsule that wirelessly relays important information about a patient's gut motor function ...
Sep 11, 2024
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Refined dietary fiber may increase risk for inflammatory bowel disease
For many people, an enjoyable summer staple food is a scoop of their favorite ice cream. What they may not know is that this creamy treat often contains refined dietary fibers, such as guar gum, that could have negative effects ...
Sep 10, 2024
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Is weight loss as simple as calories in, calories out? In the end, it may be gut microbes that make calories count
Is the adage "calories in, calories out" true? The short answer is yes, but the full story is more nuanced.
Sep 10, 2024
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Researchers compare tumor characteristics, survival outcome of different bile duct cancers
Cholangiocarcinoma (CCA) or bile duct cancer, is a rare, aggressive liver cancer with a poor prognosis, which occurs mostly in people older than age 50. It is often diagnosed when it is advanced, making successful treatment ...
Sep 10, 2024
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Proof-of-concept study demonstrates novel strategy to develop liver-targeting chimeras for disease treatment
Liver cancer ranks as the fourth most common cancer and the second leading cause of cancer-related deaths in China, with hepatocellular carcinoma (HCC) being the most prevalent type. Current treatments for liver cancer encounter ...
Sep 10, 2024
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Updated guidelines published for evaluating and managing chronic constipation
The American Society of Colon and Rectal Surgeons (ASCRS) has issued updated guidelines on how to evaluate and manage chronic constipation. The research is published in the journal Diseases of the Colon & Rectum.
Sep 10, 2024
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AI shows promise for precision inflammatory bowel disease management
Inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, are chronic conditions that significantly impact patients' quality of life. While significant advancements have been made in treatment options, ...
Sep 9, 2024
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Natural probiotic discovered in microbiomes of UK newborns
Newborn babies have one of three pioneer bacteria in their gut shortly after birth, one of which could be used to develop new personalized infant therapeutic probiotics, researchers show.
Sep 6, 2024
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Ulcers, damage to upper gastrointestinal tract linked to increased risk of Parkinson's disease
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk of developing Parkinson's disease was 76% higher among those with a history of damage to the lining of their upper gastrointestinal ...
Sep 6, 2024
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Pancreatic cancer study finds most early staging is inaccurate
Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new Cedars-Sinai Cancer study published in JAMA. The finding underscores the urgent need for advancements in diagnostic ...
Sep 5, 2024
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Study links 'forever chemical' PFOS with colorectal cancer
A recent University of Kentucky Markey Cancer Center study sheds light on how the environmental pollutant perfluorooctanesulfonic acid (PFOS) may affect our intestines and possibly increase the risk of developing colorectal ...
Sep 5, 2024
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