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Gastroenterology news

Medical research

Tuft cells act as regenerative stem cells in the human intestine, study finds

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation damage, and contribute ...

Gastroenterology

AI may help predict risk of Barrett's esophagus and esophageal cancer

Precancerous changes in the cells of the esophagus, a condition called Barrett's esophagus, is a risk factor for esophageal cancer. Barrett's esophagus is caused by gastroesophageal reflux disease (GERD), which occurs when ...

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Diseases, Conditions, Syndromes

Creating a more accurate model of inflammatory bowel disease

A research team led by Junior Associate Professor Kazuo Takayama, from the Department of Cell Growth and Differentiation, recently constructed a new model of inflammatory bowel disease using iPS cells that enables more accurate ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

How alcohol-associated liver disease differs among races

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren't equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

Neuroscience

Study reveals link between microbiome and aggression in mice

A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior ...

Diseases, Conditions, Syndromes

Cure found for rare form of inflammatory bowel disease

A rare genetic condition which causes inflammatory bowel disease can be successfully treated by bone marrow transplant, according to University of Manchester and Manchester University NHS Foundation Trust researchers.

Diabetes

Targeting the 'second brain' to fight diabetes

Patrice Cani (UCLouvain) and Claude Knauf (INSERM) have discovered a "jammer" that blocks communication between the gut and the brain, thus preventing proper regulation of sugar and causing insulin resistance in people with ...

Gerontology & Geriatrics

Could a poo transplant one day be the secret of eternal youth?

Fecal transplants could one day be used as a therapy to restore cognitive function in the elderly—according to new research from the University of East Anglia, the University of Florence and the Quadram Institute.

Diseases, Conditions, Syndromes

GI complications more common in critically ill with COVID-19

(HealthDay)—A higher rate of gastrointestinal complications, including mesenteric ischemia, occurs among critically ill patients with COVID-19 versus matched patients without COVID-19, according to a research letter published ...

Diseases, Conditions, Syndromes

Study reveals dietary fructose heightens inflammatory bowel disease

Diet remains an important part of disease prevention and management, and a new study suggests that consumption of fructose may worsen intestinal inflammation common to inflammatory bowel diseases (IBD). Led by David Montrose, ...

Gastroenterology

Microbiome-based technologies drive multibillion-dollar market

A new field of research in microbiology is transforming the way scientists see fungi, bacteria and other microorganisms. Microbiome research is so promising that it has drawn attention from funders and industry as well as ...

Oncology & Cancer

Growth factor R-spondin suppresses colorectal tumor growth

Researchers have found a surprising effect of the stem cell-regulating growth factor R-spondin in intestinal cancer. According to the newly published study, R-spondin, which enhances the growth of healthy cells in the gut, ...

Gastroenterology

Bile acids boost gut regeneration

Researchers at EPFL have made a surprising discovery about how bile acids act as signaling molecules to boost intestinal regeneration. The discovery sheds light on the role of bile acids as hormone-like molecules and opens ...

Diseases, Conditions, Syndromes

Understanding social distancing and microbial health

Social distancing is a key component of the expert-recommended strategy to reduce the spread of COVID-19. According to the World Health Organization, the SARS-CoV-2 virus passes from person to person primarily through saliva ...

Medical research

Microbes in the gut may influence metabolism

The 10 trillion bacteria living in your digestive system may not be human, but they seem to be as integral to your body as your heart or liver. A growing number of studies are finding that microbes in the gut directly influence ...