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Gerontology & Geriatrics news

Gerontology & Geriatrics

New organ-on-a-chip platform allows the testing of cancer vaccine efficacy in aging populations

Dr. Vadim Jucaud's lab at the Terasaki Institute has introduced a new organ-on-a-chip platform that recapitulates age-dependent immune responses, offering a more accurate testing bed for evaluating cancer vaccine performance ...

Psychology & Psychiatry

Friendship can be an important lifeline for older adults without children

Friendship can be one of the keys to staying healthier later in life—that was one of the key findings from new research at the University of New Hampshire that took a closer look into the growing public health concern of ...

Psychology & Psychiatry

Who are the loneliest Americans?

Middle-aged Americans are most likely to feel the pinch of loneliness in their lives these days, a new AARP survey has found.

Gerontology & Geriatrics

Age-related muscle wasting tied to cell recycling defect

Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for muscle health.

Diabetes

Diabetes drugs may help older adults slow frailty

A new study shows that older adults with type 2 diabetes who start treatment with sodium–glucose cotransporter-2 (SGLT-2) inhibitors—such as empagliflozin (Jardiance) and dapagliflozin (Farxiga)—or glucagon-like peptide-1 ...

Psychology & Psychiatry

Navigating grief in the aged care system

Grief for families in the aged care system begins long before the death of their loved ones, new research has found, highlighting the need for a systemic rethink of how grief is understood and supported.

Genetics

Why important genes 'go quiet' as we get older

The human gut renews itself faster than any other tissue: every few days, new cells are created from specialized stem cells. However, as we get older, epigenetic changes build up in these stem cells. These are chemical markers ...

Inflammatory disorders

Chronic pruritus prevalent among older adults

Chronic pruritus is prevalent among older adults and is associated with moderately impaired pruritus-specific quality of life, according to a study published online Nov. 10 in Acta Dermato Venereologica.

Alzheimer's disease & dementia

Stiff arteries may amplify early memory decline in older adults

Findings from the multisite IGNITE clinical trial suggest that arterial stiffness, which occurs when large blood vessels lose their natural flexibility, may be linked to greater injury effects to brain nerve fibers in older ...

Gerontology & Geriatrics

Bucket list wishes can make final days meaningful

Whether it's taking a trip to Disneyland or sharing a meal with a loved one, fulfilling a "bucket list" wish near the end of life offers more than fleeting joy. A new study from The University of Texas at Arlington finds ...

Oncology & Cancer

Graying hair may reflect a natural defense against cancer risk

Throughout life, our cells are constantly exposed to environmental and internal factors that can damage DNA. While such DNA damage is known to contribute to both aging and cancer, the precise connection—particularly how ...

Immunology

A missing protein may hold key to rejuvenating aging blood cells

As our hair goes gray and our muscles weaken with age, our immune system also changes. In particular, the stem cells that become blood or immune cells can develop mutations, potentially leading to cancers or other dysfunctions.

Gerontology & Geriatrics

The brain may not be a muscle, but it still needs exercise

As we age, keeping our bodies active helps us stay healthier for longer and protects against chronic disease. We can also exercise our brains to prevent age-related mental decline with activities like reading aloud, writing ...

Diseases, Conditions, Syndromes

Internal migrants in the U.S. age with fewer disabilities, study finds

A groundbreaking study analyzing data from over 5 million older Americans has found that those who migrate within the U.S. have significantly better health outcomes than those who remain in their birth state, offering compelling ...

Medical economics

Housing type linked to cardiovascular death risk in older adults

A 6-year cohort study conducted by researchers from Japan, comprising nearly 39,000 older adults found that people living in rental flats and owner-occupied detached houses face higher risks of cardiovascular death compared ...