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Inflammatory disorders news

Diseases, Conditions, Syndromes

Home-based phototherapy as effective as office-based for psoriasis

For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Inflammatory disorders

Study offers new insight into powerful inflammatory regulator

A new study in mice reveals how a protein called Brd4 boosts the inflammatory response—for better and for worse, depending on the ailment. The study is the first to show that this protein, while problematic in some circumstances, ...

Inflammatory disorders

The swollen colon—cause of chronic inflammation discovered

Researchers at the University Medical Center of Johannes Gutenberg University Mainz and the German Research Center for Environmental Health, Helmholtz Zentrum München have discovered that too much of the oncogene Bcl-3 leads ...

Inflammatory disorders

Researchers find molecular trigger for brain inflammation

Brain inflammation is a key component of multiple sclerosis, Alzheimer's, Parkinson's, ALS, and most other major neurodegenerative diseases. How inflammation starts, how it's sustained, and how it contributes to these diseases ...

Inflammatory disorders

Bitter taste receptors hold key to treating asthma

One in nine Australians, among more than 300 million people worldwide, suffer from asthma. They experience a wide range of debilitating, even life-threatening respiratory symptoms from a disease that can be controlled but ...

Inflammatory disorders

Postbiotic could lower glucose, inflammation in obesity

(HealthDay)—The bacterial cell wall-derived muramyl dipeptide (MDP) postbiotic lowers adipose inflammation and reduces glucose intolerance in obese mice, according to an experimental study published online April 20 in Cell ...

Inflammatory disorders

Experimental drug targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...

Inflammatory disorders

Tailored intervention in acute and chronic inflammation

Signal molecules called chemokines often work in tandem to recruit specific sets of immune cells to sites of tissue damage. A systematic analysis of their interactions by researchers from Ludwig-Maximilians-Universitaet (LMU) ...

Inflammatory disorders

Possible new target for treatment of multiple sclerosis found

In the relentless battle against multiple sclerosis (MS), U of A researchers recently discovered an entirely new cellular mechanism—an underlying defect in brain cells—that may to be blame for the disease, and a potential ...

Inflammatory disorders

Study brings hope of a new treatment for asthma sufferers

Improved treatments for people with severe asthma are a 'step closer' after a research team led by the University of Leicester identified a breakthrough in the cause of airway narrowing.

Inflammatory disorders

Could a ketogenic diet alleviate gout?

More than 8 million individuals in the United States have gout, a disease that can cause intense recurrent episodes of debilitating pain, inflammation, and fever. The cause of gout is the accumulation of urate crystals in ...

Inflammatory disorders

Researchers find new potential route to treat asthma

Researchers at the UNC School of Medicine believe they have isolated a protein that, when missing or depleted, can cause airway constriction, production of mucus, chest tightness, and difficulty breathing for the 334 million ...

Inflammatory disorders

Why is asthma worse in black patients?

African Americans may be less responsive to asthma treatment and more likely to die from the condition, in part, because they have a unique type of airway inflammation, according to a study led by researchers at the University ...

Inflammatory disorders

Omega-3 supplements can prevent childhood asthma

Taking certain omega-3 fatty acid supplements during pregnancy can reduce the risk of childhood asthma by almost one third, according to a new study from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) ...

Inflammatory disorders

New drug target for inflammatory disease is all the RAGE

Researchers have shown that Receptor for Advanced Glycation End Products (RAGE) helps to regulate a key signaling pathway known to promote both acute and chronic inflammation. The development of therapeutic drugs targeted ...