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Inflammatory disorders news

Inflammatory disorders

Addressing health equity in childhood asthma requires engaging affected communities

Systemic racism remains a significant challenge in efforts to address health disparities in childhood asthma. A new American Thoracic Society report provides practical frameworks to begin the research necessary to make real ...

Diseases, Conditions, Syndromes

Home-based phototherapy as effective as office-based for psoriasis

For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

New drug target for inflammatory disease is all the RAGE

Researchers have shown that Receptor for Advanced Glycation End Products (RAGE) helps to regulate a key signaling pathway known to promote both acute and chronic inflammation. The development of therapeutic drugs targeted ...

Immunology

Test used to diagnose asthma may not be accurate

A new study urges caution in the use of the mannitol challenge test for asthma in non-clinical settings. The test is considered widely applicable to detect asthma, but its accuracy outside of patients referred for specialized ...

Inflammatory disorders

Cause of inflammation in diabetes identified

Inflammation is one of the main reasons why people with diabetes experience heart attacks, strokes, kidney problems and other, related complications. Now, in a surprise finding, researchers at Washington University School ...

Inflammatory disorders

The silver lining of an inflammatory bowel disease diagnosis

Twenty-five percent of inflammatory bowel disease (IBD) patients are diagnosed as children or adolescents—at the peak of their social and educational development. Parents of newly diagnosed patients often inquire about ...

Inflammatory disorders

Dysfunctional breathing often wrongly thought to be asthma

Many people with breathing difficulties remain undiagnosed or are diagnosed wrongly as having asthma when the problem might actually be dysfunctional breathing (DB). Information and breathing exercises can help these patients. ...

Inflammatory disorders

Salmeterol + fluticasone deemed safe for childhood asthma

(HealthDay)—Children using a combination long-acting beta agonist/steroid inhaler do not have any greater risk of harm than children using a steroid inhaler alone, according to a study published in the Sept. 1 issue of ...

Inflammatory disorders

Comorbidity factors identified for exacerbation-prone asthma

(HealthDay)—Factors that are associated with exacerbation-prone asthma (EPA) have been identified, with blood eosinophils, body mass index, and bronchodilator responsiveness associated with exacerbation frequency, according ...

Inflammatory disorders

Research opens up new treatment route for inflammatory rheumatism

Enthesitis, inflammation of tendons where they attach to the bone, is a common medical problem which underlies various forms of inflammatory rheumatism. Although around 1% of the population is affected, the mechanisms driving ...

Inflammatory disorders

Asthma pill could reduce symptoms in severe sufferers

The first new asthma pill for nearly 20 years has the power to significantly reduce the severity of the condition, a study led by the University of Leicester has found.