Journal of Clinical Investigation

Medications

New drug target to treat pain from visceral organs

An approved drug for chronic constipation also relieves the pain associated with that condition. New research by Scott Waldman, MD, Ph.D., chair of pharmacology, physiology and cancer biology at Jefferson, demonstrates that ...

Medical research

Possible new way to reduce pain inspired by chickens

Stanford Medicine researchers have discovered a possible new way to treat pain without the use of opioids. By targeting a specific area of a well-known pain receptor, they were able to reduce pain sensitivity in mice without ...

Immunology

Research indicates wider benefit to AstraZeneca vaccine

A review of the COVID-19 vaccine trials indicate that adenovirus vectored vaccines may have non-specific protective effects resulting in significantly reduced all-cause mortality and non-COVID deaths, compared with mRNA based ...

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