The Journal of Medicinal Chemistry (usually abbreviated as J. Med. Chem.), is a peer-reviewed scientific journal, published since 1959 by the American Chemical Society. It was originally published as the Journal of Medicinal and Pharmaceutical Chemistry, but changed its name in 1963 to the current title. Profs. Gunda I. Georg of the University of Minnesota and Shaomeng Wang of the University of Michigan are the Editors of the journal. They took over leadership from Prof. Philip S. Portoghese of the University of Minnesota in 2012. Prof. Portoghese had served as Editor in Chief from 1972 - 2011. The Journal of Medicinal Chemistry publishes original research on the correlation of molecular structure to biological activity with a focus on the relationships of chemistry to biological activity.
A multidisciplinary team made up of doctors and scientists from the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) and the Institute for Research in Biomedicine (IRB Barcelona) has led a study, recently ...
Mar 30, 2023
0
32
Building a new precision cancer treatment comes with no shortage of scientific challenges. Now, a group of University of Florida researchers have made a significant discovery in the effort to develop potent, highly targeted ...
Feb 20, 2023
0
68
Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize ...
Jan 30, 2023
0
35
While chemotherapy drugs can be lifesaving, they don't work for all patients or for all cancers. But a team of UTM researchers is looking at new ways to use special types of light to target cancer cells resistant to current ...
Sep 14, 2022
0
85
Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent inflammation and assault to the kidney. The disorder leads to kidney disease, itself a pathway to kidney failure, also known ...
Aug 22, 2022
1
264
Innovations in cancer immunotherapy have achieved clinical success by considerably increasing the survival rate of patients undergoing cancer treatment. However, there still exists an unmet medical need due to the low response ...
May 31, 2022
0
9
An enzyme that has been identified as instrumental in the progression of many types of cancer is meeting its match in inhibitors synthesized and evaluated by University of Colorado (CU) Cancer Center researchers.
Apr 7, 2022
0
23
A potent and selective enhancer of zeste homolog 2 (EZH2) inhibitor IHMT-EZH2-115 was recently discovered by researchers led by Prof. Liu Qingsong from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences ...
Nov 1, 2021
0
9
Virtual reality (VR) technology enables scientists to create 3D models of an object and then virtually go "inside" to look around to better understand its structure and function.
Oct 28, 2021
0
89
Ischemic stroke, the second leading cause of death worldwide, occurs when a vessel to the brain is blocked, reducing blood flow to the brain and depriving it of critical supplies of oxygen and nutrients. This process leads ...
Oct 8, 2021
0
51
