Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells decide ...
May 3, 2019
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Mount Sinai researchers have broken new ground in the understanding of the MDM2 gene—which is often overexpressed in cancer—finding that when it acts with a specific protein, it can lead to cancer cell death. The study ...
May 1, 2019
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Cancer cells have various tricks up their metaphorical sleeves to survive in the face of chemotherapy, radiotherapy and other cancer treatments. Now researchers at Mayo have decoded one of those tricks using cell lines and ...
Apr 30, 2019
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Embryonic stem cells (ESC) have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body. The embryonic stem cell state is established and maintained by multiple regulatory ...
Apr 17, 2019
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St. Jude Children's Research Hospital scientists have cracked the mystery surrounding the most common genetic cause of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The research suggests possible new approaches ...
Apr 10, 2019
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St. Jude Children's Research Hospital scientists have found that the enzymes ULK1 and ULK2 play a key role in breaking down cell structures called stress granules, whose persistence leads to toxic buildup of proteins that ...
Apr 10, 2019
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Genetic mutations that drive the development of a common type of childhood leukaemia can be traced back to errors by the immune system during the production of antibodies.
Mar 22, 2019
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Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...
Mar 20, 2019
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Fat, biologically speaking, is not a bad thing. Fatty acids—the molecular building blocks for body fat—are crucial to the formation of cell walls and for storing energy in the form of glycerolipids. Now, Rockefeller scientists ...
Mar 7, 2019
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A team of researchers from the MRC Weatherall Institute of Molecular Medicine at Oxford University has developed a new technique that allows scientists to reliably track genetic errors in individual cancer cells, and find ...
Feb 12, 2019
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