Nature Methods

Genetics

Scientists genetically decode rare kidney disease

When Dr. Bodo Beck first saw the three children of a family who had fled Syria sitting in his consultation room at University Hospital Cologne, the human geneticist was surprised. His genetic analysis diagnosed Bartter syndrome ...

Diseases, Conditions, Syndromes

New tool expands the horizons for neuron sequencing

Ever since 19th-century neuroanatomist Santiago Ramón y Cajal discovered the brain's beautifully complex neurons—what he referred to as "the mysterious butterflies of the soul"—neuroscientists have sought to characterize ...

Neuroscience

Reconstructing brain connectivity using 3D images

Initiated in 2015 and led by the Allen Institute for Brain Science, BigNeuron is an international initiative that brings together computer scientists and neuroscientists from a dozen institutions. Its goal is to develop a ...

Neuroscience

A three-photon microscope for capturing deep-brain images

A research team at China's Peking University has made a new breakthrough in multiphoton microscopy by developing a miniature three-photon microscope that has successfully captured deep-brain images of freely moving mice.

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