Neurobiology of Disease is a major international journal at the interface between basic and clinical neuroscience. The journal provides a forum for the publication of top quality research papers on: molecular and cellular definitions of disease mechanisms, the neural systems and underpinning behavioral disorders, the genetics of inherited neurological and psychiatric diseases, nervous system aging, and findings relevant to the development of new therapies.
When brain oxygenation is cut off for a prolonged period, the electrical activity of the cerebral cortex is quickly reduced to zero. But that's not the end of the story.
Dec 12, 2023
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Northwestern Medicine scientists have discovered two ways to preserve diseased upper motor neurons that would normally be destroyed in ALS, based on a study in mice. Upper motor neurons initiate movement, and they degenerate ...
Feb 24, 2023
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The locus coeruleus is among the first brain regions to degenerate in Alzheimer's and Parkinson's disease, physicians and scientists have known. But why this area is so vulnerable is less understood.
Sep 1, 2022
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Although Alzheimer's disease is one of the most studied pathologies due to its high prevalence, the molecular changes that cause astrocytes, a type of brain cell, to become reactive astrocytes, manifesting a very pronounced ...
Mar 18, 2022
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Around 1 percent of the world's population lives with epilepsy; yet only 65 percent of epilepsy patients can manage their symptoms with medication. Currently, surgically removing the lesion in the brain responsible for the ...
Jan 17, 2022
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187
Fragile X syndrome, or FXS, a leading genetic cause of autism, affects around one in 4,000 males and one in 6,000 females. Its symptoms include increased anxiety, intellectual disability, repetitive behaviors, social communication ...
Dec 13, 2021
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Scientists at Oregon Health & Science University have identified a naturally occurring mutation in nonhuman primates that closely resembles a rare neurodegenerative disease in people.
Aug 6, 2021
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394
Scientists have successfully treated flies displaying behavioral problems linked to newly discovered schizophrenia-associated genes in humans, using common anti-psychotics.
May 19, 2021
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Rearing its head in infancy, Christianson Syndrome is a rare disorder whose symptoms include intellectual disability, seizures and difficulty standing or walking. Although it is becoming increasingly diagnosed, with little ...
Jun 28, 2019
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Worldwide, 50 million people are living with Alzheimer's disease and other dementias. According to the Alzheimer's Association, every 65 seconds someone in the United States develops this disease, which causes problems with ...
Apr 23, 2019
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