Oncogene is a peer-reviewed scientific journal published by the Nature Publishing Group addressing cancer cell genetics and the structure and function of oncogenes.
Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer cells using only factors that are commonly detected in actual human patients. ...
Sep 07, 2021
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MUSC Hollings Cancer Center researchers discovered a novel mechanism showing how a certain gene mutation can allow tumors to evade detection by the immune system in colorectal cancer patients. The study, which was published ...
Sep 02, 2021
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Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new ...
Jul 14, 2021
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Combining chemotherapy and BRAF oncogene inhibitors is an effective strategy for fighting metastatic melanoma, the leading cause of death from skin cancer in the world. This has been demonstrated in a study by researchers ...
Jul 13, 2021
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Hypoxia, or the inadequate oxygenation of a tissue, is a condition occurring frequently in all solid tumors such as melanoma skin cancer. Melanoma cells are not only able to survive oxygen deprivation, but also to use it ...
Jun 21, 2021
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Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it. Anti-estrogen ...
Apr 24, 2021
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Breast cancer is harmful enough on its own, but when cancer cells start to metastasize—or spread into the body from their original location—the disease becomes even more fatal and difficult to treat.
Mar 11, 2021
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Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets. They report in the ...
Mar 04, 2021
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Gastrointestinal stromal tumors (GISTs) are a subytpe of cancers known as sarcomas. GIST is the most common type of sarcoma with approximately 5,000 to 6,000 new patient cases annually in the United States. GIST cannot be ...
Feb 18, 2021
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SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes ...
Jan 29, 2021
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