Science Signaling

Oncology & Cancer

Researchers characterize mechanism of action of CAR T cells

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells. ...

Medical research

Why too much DNA repair can injure tissue

DNA-repair enzymes help cells survive damage to their genomes, which arises as a normal byproduct of cell activity and can also be caused by environmental toxins. However, in certain situations, DNA repair can become harmful ...

Diseases, Conditions, Syndromes

Infinite hug mechanism may be key to lung fibrosis

Researchers have long known that fibrosis – scarred tissue and organs – is caused by a wound healing mechanism that goes awry beyond normal wound repair. Now, a group of researchers at the University of Toronto's Faculty ...

Oncology & Cancer

Scientists identify weak point in deadly eye melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma ...

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