Structure

Structure is a peer-reviewed scientific journal founded by Wayne A. Hendrickson, Carl-Ivar Brändén and Alan R. Fersht in September 1993. It focuses on protein structure and related issues. The journal is published monthly by Cell Press. The current editors are Christopher D. Lima and Andrej Sali.

Publisher
Cell Press
Country
United States
History
1993–present

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Inflammatory disorders

Scientists reveal cellular clockwork underlying inflammation

Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation—a discovery that could have important implications for the treatment of allergies, ...

Ophthalmology

Researchers report startling glaucoma protein discovery

A discovery in a protein associated with glaucoma was so unheard of that for over two years, researchers ran it through a gauntlet of lab tests and published a new research paper on it. The tests validated what they initially ...

Neuroscience

Study shows how mutations disrupt ALS-linked protein

In amyotrophic lateral sclerosis, aggregates of the protein TDP-43 are almost always found in afflicted neurons and glial cells. Meanwhile, about 50 ALS-linked mutations are known to affect a particular region of TDP-43. ...

Oncology & Cancer

First 3-D map of cell-building protein linked to cancer

Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.

Medical research

Researchers describe building blocks of HIV's protective shell

The genome of the HIV-1 virus is protected by a conical-shaped protein shell called a capsid, which performs many functions crucial to viral infection—shielding the virus from the immune system, attaching to cell's transport ...

Diseases, Conditions, Syndromes

Computer simulations reveal every curve of the dengue viral envelope

The near-spherical outer structure of the dengue virus has been recreated in remarkable detail by a team of bioinformaticians in Singapore. The virtual model could show researchers how the virus fuses with and infects human ...

Oncology & Cancer

Putting the brakes on tumor stealth

New research undertaken at Monash University has shed new light on how some cancers are able to escape our immune system.

Immunology

Engineering the immune system to kill cancer cells

In late 2015, former President Jimmy Carter announced that he was free of the metastatic melanoma that had spread to his liver and brain. In addition to surgery and radiation, Carter was treated with an immunotherapy drug, ...

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