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Clinical pharmacology news
GLP-1 prescriptions for new mothers have increased sharply
More U.S. women are being prescribed GLP-1 medications after giving birth, particularly those diagnosed with diabetes, according to new research from the USC Schaeffer Center for Health Policy & Economics.
9 hours ago
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New triple agonist drug produces substantial weight loss in diabetic patients
New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28—Oct 2) and appearing in The Lancet shows that treatment with the new triple agonist ...
Oct 1, 2026
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Nail detachment over four times more common among GLP-1 users, first controlled study finds
Nail detachment is more than four times as common among people taking GLP-1 receptor agonists as among comparable people with obesity or type 2 diabetes who are not taking the drugs, according to the first controlled study ...
Sep 30, 2026
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Experimental drug may reduce lymphedema swelling and scarring
Matthew Holbreich was a senior in college when the swelling started. He originally thought he had injured his left leg playing squash, but the intensity of the swelling scared him. After seeing a few doctors in Boston, where ...
Sep 30, 2026
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Experimental obesity drug targets appetite through amylin, offering potential alternative to GLP-1 therapies
New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2), and published in The Lancet Diabetes & Endocrinology shows that weekly injections ...
Sep 30, 2026
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Activating 'energy saver' mode significantly extends lives of animals in preclinical study
Scientists have successfully used a drug to prolong the lifespan of several species of animals, in some cases by more than 25%. The study, published in Aging Cell, found strong evidence that activating a protein that governs ...
Sep 30, 2026
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Trevogrumab (anti-myostatin) can help preserve lean mass during and after semaglutide-induced weight loss
New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, and in press at The Lancet shows that trevogrumab, which inhibits a protein that ...
Sep 30, 2026
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Combination therapy emerges as possible treatment for an aggressive form of kidney cancer
A genetic vulnerability in clear cell renal cell carcinoma, the most aggressive type of kidney cancer, may lend itself to a combination treatment strategy that causes the cancer cells to self-destruct, according to recent ...
Sep 30, 2026
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Higher GLP-1 costs lead to lower adherence
Semaglutides, or GLP-1s, can produce substantial weight loss if individuals adhere to their doctor's instructions. But a new study from the University of Georgia suggests patients aren't taking the weight loss medication ...
Sep 30, 2026
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New investigational drug delivers up to 23.3% weight loss in people with obesity and diabetes
New data from a phase 2b study being presented at the 2026 annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept. 28–Oct. 2), show that, for people living with obesity and type ...
Sep 30, 2026
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Long‑acting medicines could make daily tablets a thing of the past for some patients
For millions of people around the world, managing a long-term health condition means remembering to take medicines every day, often for years. But advances in long-acting medicines mean that some treatments now need to be ...
Sep 30, 2026
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Research offers new hope for those at higher risk of Alzheimer's disease
A new study from the University of Missouri offers hope for those who are at significantly higher risk of developing Alzheimer's disease later in life.
Sep 30, 2026
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Real-world findings suggest GLP-1 drugs offer health benefits for young people with diabetes
New research presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, from Sept. 28–Oct. 2 examined the real-world use of GLP-1 receptor agonist (GLP-1 RA) drugs in children ...
Sep 30, 2026
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Two charged in scheme to sell counterfeit Ozempic—how you can spot fake meds
Federal prosecutors have charged two people in an alleged scheme to bring fake versions of the type 2 diabetes drug Ozempic from China and sell them to U.S. distributors.
Sep 30, 2026
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A deadly fungus may not live to see the last of us
The battle lines have finally shifted in the war against a deadly fungal disease.
Sep 30, 2026
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Machine learning toolkit can improve odds of drug development success
Southwest Research Institute (SwRI) is using a generative artificial intelligence (AI) tool to improve pharmaceutical development outcomes. The SwRI-developed GAMES, or Generative Approaches for Molecular Encodings, uses ...
Sep 30, 2026
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Benzodiazepine prescriptions dropped sharply in the US over the past decade, research finds
The number of prescriptions dispensed for benzodiazepines like Xanax and Valium declined in the United States over the past 10 years, potentially suggesting that doctors have become more cautious about prescribing these sedatives, ...
Sep 30, 2026
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Model reveals strategies to modify the tumor microenvironment and improve cancer therapy
Researchers from Mass General Brigham and the University of Cyprus have developed a mathematical model to better understand how the tumor microenvironment affects the delivery and effectiveness of a new type of cancer therapy ...
Sep 30, 2026
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Promising therapy for fatty liver disease reduces fat, inflammation, and scarring in preclinical models
For millions of people living with metabolic dysfunction-associated steatohepatitis (MASH), treatment options remain limited. The progressive form of fatty liver disease develops when excess fat accumulates in the liver, ...
Sep 29, 2026
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Severe withdrawal cases point to growing medetomidine use
A powerful veterinary sedative, medetomidine, is increasingly appearing in street supplies of the already deadly opioid fentanyl, and the number of patients suffering from medetomidine withdrawal has quadrupled in recent ...
Sep 29, 2026
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Anti-cancer molecules show promise in the fight against malaria
Molecules known for their anticancer activity have proven effective against Plasmodium falciparum, the parasite that causes malaria. Researchers at the University of São Paulo's School of Pharmaceutical Sciences (FCF-USP) ...
Sep 29, 2026
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Menthol enhances the strength and duration of nicotine's effects in rats
Menthol, a common flavoring for traditional cigarettes and e-cigarettes, may do more than change how nicotine tastes or feels. New research published in ACS Chemical Neuroscience reports that male rats exposed to menthol-containing ...
Sep 29, 2026
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New opioid up to 10 times stronger than fentanyl spreading across US
A powerful new lab-made opioid is moving through the illegal U.S. drug supply, and federal officials warn it could keep spreading.
Sep 29, 2026
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First national estimate identifies nearly 110,000 medical cannabis caregivers
A national analysis found that the number of clinicians authorized to approve medical cannabis use in the United States increased to more than 35,000 in 2024. The study also provides the first nationwide estimate of medical ...
Sep 29, 2026
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Scientists overcome key barrier to self-amplifying vaccines
Scientists at Queen Mary University of London have found a way to overcome cells' natural defenses against self-amplifying mRNA vaccines, allowing the cells to produce significantly more of the target protein. The findings ...
Sep 28, 2026
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