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Clinical pharmacology news

Newly identified molecule could help regulate sleep

Sleep is known to be essential for survival, as it allows both humans and other animals to rest, while the brain consolidates memories and clears out metabolic waste products. For many people worldwide, however, falling asleep ...

Natural compounds against sarcoma: Which one shows the greatest potential?

Curcumin, berberine and other plant-derived compounds have long attracted scientific interest because of their anti-inflammatory and anticancer properties. A new study by researchers from Wroclaw Medical University and the ...

GLP-1 diabetes drugs linked to up to 68% higher hair loss risk

The use of glucagon-like peptide-1 (GLP-1) receptor agonists to treat type 2 diabetes and obesity is associated with an increased risk of hair loss (alopecia) in adults with type 2 diabetes, a study published by The BMJ finds. ...

Viagra may reduce cancer metastasis, study shows

Viagra was originally developed to treat high blood pressure and chest pain caused by reduced blood flow to the heart, but over the past three decades it has become the world's best-known therapy for erectile dysfunction. ...

One of the oldest psychedelics meets modern brain imaging

For millennia, people have used the psychedelic mescaline as a spiritual and religious tool. Mescaline is a naturally occurring chemical found in cacti, mainly peyote cacti, that are located in the Southwest United States ...

Researchers study barriers to GLP-1 insurance coverage

Despite growing evidence that GLP-1 medications improve health and are worth their cost, many insurance plans still limit coverage. University of Mississippi researchers are examining why and where that leaves patients.

Q&A: Psychedelics, cannabis, GLP-1s and drug policy changes

From headlines and social media, psychedelic therapies, cannabis use and GLP-1 medications have seemingly become commonplace overnight, but the science underlying these treatments and the pathway to drug approval are often ...

Engineered probiotic heads to human trials

A probiotic bioengineered by UBC Okanagan researchers to thrive in the inflamed gut is set to enter human clinical trials in Australia this summer, capping a decade-long effort to turn a beneficial bacterium into a treatment ...

FDA approves another over-the-counter naloxone nasal spray

The U.S. Food and Drug Administration has approved another over-the-counter intranasal naloxone product, Rextovy (naloxone hydrochloride), for the emergency treatment of opioid overdose. The nonprescription approval was granted ...