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Clinical pharmacology news

GLP-1 prescriptions for new mothers have increased sharply

More U.S. women are being prescribed GLP-1 medications after giving birth, particularly those diagnosed with diabetes, according to new research from the USC Schaeffer Center for Health Policy & Economics.

New triple agonist drug produces substantial weight loss in diabetic patients

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28—Oct 2) and appearing in The Lancet shows that treatment with the new triple agonist ...

Experimental drug may reduce lymphedema swelling and scarring

Matthew Holbreich was a senior in college when the swelling started. He originally thought he had injured his left leg playing squash, but the intensity of the swelling scared him. After seeing a few doctors in Boston, where ...

Higher GLP-1 costs lead to lower adherence

Semaglutides, or GLP-1s, can produce substantial weight loss if individuals adhere to their doctor's instructions. But a new study from the University of Georgia suggests patients aren't taking the weight loss medication ...

Severe withdrawal cases point to growing medetomidine use

A powerful veterinary sedative, medetomidine, is increasingly appearing in street supplies of the already deadly opioid fentanyl, and the number of patients suffering from medetomidine withdrawal has quadrupled in recent ...

Scientists overcome key barrier to self-amplifying vaccines

Scientists at Queen Mary University of London have found a way to overcome cells' natural defenses against self-amplifying mRNA vaccines, allowing the cells to produce significantly more of the target protein. The findings ...

Folic acid does not elevate formaldehyde in mice and humans

Folic acid—an essential vitamin added to flour and cereals and prescribed at high doses for cancer patients and people with blood disorders—does not elevate toxic formaldehyde in the body, according to a new study of mice ...

Egyptian group developing Ebola vaccine

An Egyptian pharmaceutical firm is developing a potential vaccine against the deadly Ebola strain raging in the Democratic Republic of Congo (DRC), it announced Thursday.

New mRNA immunotherapy eliminates pancreatic tumors in mice

Inspired by the work of the RNA Therapeutics Institute at UMass Chan Medical School and the development of the COVID vaccine, Marcus Ruscetti, Ph.D., and Chaitanya Naimesh Parikh, Ph.D. '26, have developed an immunotherapy ...