Why some skin cancers defy immunotherapy—and how to fight back
A study has revealed why some patients don't respond to immune checkpoint blockade (ICB) therapy for solid cancer tumors and identifies a new combination treatment.
Jun 2, 2025
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Amino Acids, Peptides, and Proteins: News and Research on Antibodies, Monoclonal
MeSH tree: D12.776.124.486.485.114.224
Combination therapy extends survival in advanced skin cancer, trial finds
In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the combination of the immunotherapy drug avelumab and targeted agent cetuximab had almost four times longer ...
Jun 1, 2025
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Antibody-mediated protection mechanism expands tuberculosis treatment options
Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ability to fight Mycobacterium tuberculosis (Mtb), the bacteria responsible for tuberculosis (TB). ...
May 30, 2025
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Early detection is key to improving treatment of uveitis, a global leading cause of vision loss
New treatment guidance has been developed to help doctors tackle uveitis—one of the leading causes of vision loss. The new clinical guidance, by a team at the University of Bristol, aims to help thousands of sufferers keep ...
May 28, 2025
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Attaching fluorescing dye to oral cancer proteins could yield powerful prediction tool for varying cancer types
Some 10 million people in the U.S. have oral premalignant disease, a group of diseases that show up as red patches, white patches or rough patches in the mouth and that might—or might not—develop into cancer.
May 27, 2025
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Inexpensive HIV drug can improve vision in patients with common diabetes complication, clinical trial suggests
An inexpensive, long-approved HIV drug can improve vision in patients with a blinding complication of diabetes more effectively and at a much lower cost than many existing treatments, an initial clinical trial suggests. Further, ...
May 27, 2025
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Rediscovering denosumab: From osteoporosis medication to a possible treatment for breast cancer
Science and society collaboration is essential for scientific progress, especially in the health and biomedical fields where basic researchers, clinicians and patients are involved, as shown by the initial results of D-BIOMARK. ...
May 16, 2025
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Study links inflammation to reduced motivation and brain circuit changes in schizophrenia
A new study from Emory University has identified a biological connection between inflammation and deficits in motivation in individuals with schizophrenia, offering new hope for treating symptoms that have long been resistant ...
May 16, 2025
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Bevacizumab ovarian cancer trial: Real-world impact?
A real-world study based on information from an electronic health records–derived database reveals limited benefits of adding bevacizumab to first-line chemotherapy for patients with ovarian cancer, consistent with previous ...
May 12, 2025
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Man bitten by snakes 200 times may help create new antivenom
Tim Friede has survived hundreds of snakebites—on purpose. For nearly two decades, he let some of the world's most dangerous snakes sink their fangs into his arms, all for science.
May 10, 2025
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