MeSH tree: D12.776.124.790.651.114.244
For more than 20 years, Harvard infectious disease specialist Roger Shapiro has fought HIV on the ground in Botswana, where the rate of infection exceeded 30% in some areas of the country in the 1990s.
Aug 20, 2025
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In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a series of vaccines can coax the immune system to produce powerful antibodies capable of blocking a ...
May 27, 2025
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A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional approaches haven't worked—largely ...
May 15, 2025
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Worldwide, an estimated 40 million people live with HIV. Two-thirds of this group are on the African continent. In 2023, more than 600,000 people died from HIV-related causes and 1.32 million were infected. There is no vaccine ...
May 15, 2025
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Lipids are the fatty molecules that make up cellular membranes, creating a protective barrier that regulates what enters and exits the cell. Until recently, scientists believed antibodies couldn't safely target lipids without ...
May 2, 2025
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If the past four decades have taught us anything about HIV, it's to adjust our expectations—despite enormous progress in controlling the virus, no treatment can yet completely eradicate HIV once it has taken hold. But promising ...
Mar 28, 2025
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In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with ...
Sep 12, 2024
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HIV has proven a hard target for vaccine design. The most promising approach, germline-targeting (GT), proposes a series of immunizations: a first shot to activate inexperienced B cells—antibody-producing white blood cells—followed ...
May 21, 2024
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