Antiviral defense gained at the cost of autoimmunity risk, study shows
Why do genetic variants that increase the risk of autoimmune disease remain so common in the population?
17 hours ago
0
5
Amino Acids, Peptides, and Proteins: News and Research on DNA-Binding Proteins
MeSH tree: D12.776.260
How losing the 'guardian of the genome' can damage DNA and drive cancer
A new study finds that when p53, one of the most important cancer-protecting genes, stops working, cells produce too much RNA and consume excessive amounts of the building blocks needed to copy their DNA. This shortage disrupts ...
Sep 7, 2026
0
12
'Molecular glue' redirects a cancer-driving protein to activate cell death
A two-headed molecule designed by Stanford Medicine researchers hijacks one of the most common protein drivers of B-cell lymphoma, flipping it from its role as a promoter of cell growth into an arbiter of cell death. In mice, ...
Aug 20, 2026
0
38
New mechanism may help predict and improve macrophage-targeted cancer immunotherapy
Immunotherapy that targets tumor-associated macrophages, a type of immune cell in the tumor microenvironment, works only if the cells have a functional system of molecules that enables them to respond to the treatment. This ...
Aug 14, 2026
0
13
Rb's unexpected activation of estrogen-responsive genes could explain breast cancer treatment resistance
Researchers at Peter Mac have discovered why breast cancer treatment stops working for some patients, uncovering the unexpected role of one of the body's most important cancer-fighting proteins. The study, published in Nature, ...
Aug 13, 2026
0
20
New Tfr cell model uncovers molecular switches that restrain antibody responses
For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular regulatory T cells (Tfr cells) play a key role in this process by limiting excessive immune responses ...
Jun 25, 2026
0
3
Stress-linked gut viruses may help tumors evade the immune system
Chronic psychological stress can help tumors evade immune attack through a chain of molecular events involving gut bacteria and viruses within those bacteria, according to a study led by Weill Cornell Medicine investigators. ...
Jun 25, 2026
0
4
Scientists unlock gut-healing power of fruits and nuts paired with the right gut microbes
University of Louisville researchers have discovered how a naturally occurring microbial compound may help protect the gut and support future treatment strategies for inflammatory bowel disease (IBD).
Jun 24, 2026
0
709
Hidden PIM1 pathway helps prostate cancer survive treatment, pointing to new drug strategy
Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression.
Jun 16, 2026
0
9
Why breast cancer becomes more deadly with age
Researchers at Georgetown's Lombardi Comprehensive Cancer Center have identified a mechanism that may help explain a key reason why older people experience worse outcomes from breast cancer. The study implicates RAGE (Receptor ...
May 15, 2026
0
25
