Experimental painkiller could outsmart opioids—without the high
An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids.
May 19, 2025
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Amino Acids, Peptides, and Proteins: News and Research on Adaptor Proteins, Signal Transducing
MeSH tree: D12.776.476.024
Immune system proteins involved in severe parasitic disease identified
New insights into the mechanisms that cause more severe cases of schistosomiasis—a disease caused by parasitic worms and second only to malaria in terms of potential harm—have been revealed by researchers at Penn State.
Apr 16, 2025
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New genetic therapy shows promise for motor neuron disease and frontotemporal dementia
Macquarie University neuroscientists have developed a single-dose genetic medicine that has been proven to halt the progression of both motor neuron disease (MND) and frontotemporal dementia (FTD) in mice—and may even offer ...
Feb 16, 2024
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From soft tissue to stiff leather: Understanding the role of paxillin in liver fibrosis
Currently, the United States lacks FDA-approved treatments for liver fibrosis, highlighting the critical need to understand the cellular biology and pathways associated with this condition.
Nov 1, 2023
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Could drops replace eye injections for retina disease?
A new study suggests that eye drops developed by Columbia University researchers could be a more effective–and comfortable–therapy for a common eye disease currently treated with injections into the eye.
Jul 13, 2023
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NLRP12 as a new drug target for infection, inflammation and hemolytic diseases
Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to ...
Jun 1, 2023
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The impact of cortactin in cancer progression
A new editorial paper titled " Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway" has been published in Oncotarget.
Apr 4, 2023
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New molecular blocker halts breast cancer metastasis, says study
An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory ...
Jan 17, 2023
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The tumor environment can affect breast cancer prognosis
The environment in which breast cancer arises—the interplay between the patient's BMI, tumor size and cancer-specific proteins—is of importance for the prognosis. This is shown in a study from Lund University in Sweden. The ...
Aug 25, 2022
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Gene therapy approach shows promise in treating ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control.
Aug 2, 2022
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