MeSH tree: D12.776.476
Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of ...
Mar 27, 2026
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Drugs that block enzymes called tyrosine kinases are among the most effective targeted therapies for cancer. However, they typically work for only 40% to 80% of the patients who would be expected to respond to them. In a ...
Mar 26, 2026
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Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney disease following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms that may serve as potential ...
Mar 23, 2026
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Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced back to tiny changes in ...
Mar 22, 2026
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T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the earliest moments of that ...
Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival rates have steadily declined over the last few decades. The most aggressive subtypes are a significant ...
Mar 16, 2026
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In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular signaling proteins as a strategy ...
Mar 6, 2026
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Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...
Mar 5, 2026
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Colorectal cancer is the third most common cancer in the United States. Although screening has led to a decrease in incidence over the past 20 years, early-onset colorectal cancer has been rising. Despite advances in surgery ...
Mar 4, 2026
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When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, new research finds. Michigan State University scientists have found that cocaine changes how the ...
Mar 4, 2026
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