Most Alzheimer's cases linked to variants in a single gene
Potentially more than 90% of Alzheimer's disease cases would not occur without the contribution of a single gene (APOE), according to a new analysis led by UCL researchers.
Jan 9, 2026
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Amino Acids, Peptides, and Proteins: News and Research on Amyloid beta-Protein Precursor
MeSH tree: D12.776.543.039
How an antiviral defense mechanism may lead to Alzheimer's disease
One of the main proteins that contributes to Alzheimer's disease is called phospho-tau (p-tau). When p-tau gets too many phosphate groups attached to it (a process called hyperphosphorylation), it starts to stick together ...
Dec 17, 2025
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Cerebrospinal fluid motion in the brain captured in remarkable detail
Cerebrospinal fluid (CSF) is a clear and watery liquid that flows in and around the brain and spinal cord. Its functions include protecting parts of the nervous system, delivering nutrients and removing metabolic waste.
Newly discovered Alzheimer's mechanism is linked to brain inflammation
Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.
Oct 23, 2025
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Large PET scan study links genetics, gender and age to Alzheimer's tau buildup
In a study led by Lund University and the Amsterdam University Medical Center, researchers used PET to analyze aggregates of tau pathology in more than 12,000 people from all over the world. The study—the largest ever of ...
Sep 17, 2025
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UK aims to transform Alzheimer's diagnosis with blood test trial
UK researchers on Wednesday announced the trial of a blood test for Alzheimer's which it is hoped will transform diagnosis of the disease.
Sep 10, 2025
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First participant with Down syndrome joins Alzheimer's prevention trial
Researchers have dosed the first participant in a clinical trial of an investigational medicine designed to lower the amount of amyloid precursor protein (APP) for the potential treatment of Alzheimer's disease (AD), which ...
Apr 11, 2025
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COVID-19 linked to increase in biomarkers for abnormal brain proteins
Researchers have uncovered a link between COVID-19 and blood markers linked to faulty proteins in the brain. The analysis, led by researchers at Imperial College London and the UK Dementia Research Institute, found that people ...
Jan 30, 2025
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Red meat consumption raises risk of dementia and cognitive decline, study suggests
Red meat consumption is an established risk factor for chronic conditions, including cardiovascular disease and type 2 diabetes. A new study by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, ...
Jan 15, 2025
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Disruption of mechanical signaling in brain could be basis for development of Alzheimer's disease, study proposes
A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease. Researchers have shed new light on how mechanical signaling in the brain is disrupted ...
Nov 27, 2024
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