MeSH tree: D23.101.100.150
Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial ...
Feb 7, 2024
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Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR ...
Jan 17, 2024
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Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks ...
Jan 3, 2024
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Medical investigators are theorizing that a combination of two treatments that activate myeloid cells may effectively treat a recalcitrant form of pancreatic cancer that thwarts conventional immunotherapy.
Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated. However, many patients develop resistance to these treatments due ...
Nov 16, 2023
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A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. Scientists in the Perelman School of Medicine at the University ...
Aug 31, 2023
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A new nuclear medicine therapy can cure human non-Hodgkin's lymphoma in an animal model, according to research published in the April issue of the Journal of Nuclear Medicine. A single dose of the radioimmunotherapy, [177Lu]Lu-ofatumumab, ...
Apr 11, 2023
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With new findings that the immune system plays a key role in conditions affecting the heart or blood vessels, options emerge for new cures.
Apr 3, 2023
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Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (February 4), has shown that changing how tightly an antibody binds to a target could improve treatments ...
Feb 1, 2023
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