MeSH tree: D23.529.374.465.518
Developing effective immunotherapies for acute myeloid leukemia (AML) has long been hampered by a critical challenge: Therapy directed at killing the leukemia cells may also harm the body's ability to make new, healthy blood ...
May 12, 2026
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A group of scientists in China has revealed a novel mechanism whereby a short form of IL-18, generated by caspase-3 cleavage in tumor cells, activates natural killer (NK) cells to suppress tumor growth, offering new therapeutic ...
Feb 6, 2025
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Immunotherapeutic approaches have substantially improved the treatment of patients with advanced malignancies. However, most advanced and metastatic malignancies remain incurable and therefore represent a major unmet need.
Oct 4, 2024
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While CAR T cell therapy has revolutionized treatment for many blood cancers, including non-Hodgkin lymphoma (NHL), many patients who receive CAR T cell therapy do not experience a long-term remission. For those whose cancers ...
Jun 1, 2024
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A new research paper titled "IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts" has been published in Aging.
Feb 13, 2024
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Sepsis—when an infection causes the immune system to improperly target the body—is one of the leading causes of death in the ICU.
Jan 8, 2024
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H. pylori—short for Helicobacter pylori—colonizes the stomach and is known to be linked to the development of stomach cancer. It is estimated that over half of the world's population is infected with H. pylori, making it ...
Nov 29, 2023
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A new research paper titled "Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids" has been published in ...
Nov 8, 2023
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A new study from Tulane University has identified a new treatment for a chronic immune system disease that can prevent children from eating.
Jul 31, 2023
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A study led by Daniel Jane-Wit, MD, Ph.D., a Yale School of Medicine associate professor of medicine (cardiology) and of immunobiology, could revolutionize our understanding of immune signaling. The study, published May 24 ...
Jun 14, 2023
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