MeSH tree: G04.835.925
The development of hepatocellular carcinoma, liver cancer, is known to involve the abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.
Jun 28, 2023
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37
Infants born with Down syndrome, the genetic condition caused by an extra copy of chromosome 21, or trisomy 21, are highly predisposed to congenital heart defects. It is estimated that nearly half of newborns with Down syndrome ...
Jun 21, 2023
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49
There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the brain's precious gray matter.
Jun 20, 2023
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90
What if Alzheimer's disease left its mark on the embryo? Khadijeh Shabani and her colleagues from the Brain Development team led by Bassem Hassan (Inserm) at Paris Brain Institute show that the amyloid precursor protein (APP) ...
Jun 16, 2023
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110
The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.
May 23, 2023
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474
Ischemic stroke, caused by a blockage of blood flow to the brain, is a common cause of death and disability. Treatments are urgently needed to improve patient outcomes, because recovery currently depends largely on the timely ...
May 11, 2023
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70
Researchers with the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborators have shown that immature natural killer (NK) cells are present in patients with triple-negative ...
Mar 28, 2023
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274
A Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.
Jan 10, 2023
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134
A new research paper titled "Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression" has been published in Oncotarget.
Jan 5, 2023
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48
Scientists have revealed the inner workings of a key protein involved in a wide range of cellular processes—potentially paving the way for better and less toxic cancer drugs.
Nov 23, 2022
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75
