MeSH tree: A11.284.149.165.420.297
A University of California San Diego-led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms ...
Jan 26, 2026
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Our skin protects us from everyday mechanical stresses, like friction, cuts, and impacts. A key part of this function—standing as a bulwark against the outside world—is the skin's amazing ability to regenerate and heal. But ...
Oct 13, 2025
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Researchers at the Hubrecht Institute have laid the foundation for the development of a gene therapy for the genetic heart disease arrhythmogenic cardiomyopathy (ACM). Their approach, based on replacement of the PKP2 gene, ...
Dec 7, 2023
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Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2,000 to 5,000 people worldwide. Researchers from the group of Eva van ...
Mar 22, 2023
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Researchers from the group of Eva van Rooij in collaboration with the UMC Utrecht identified a new mutation that leads to the cardiac disease arrhythmogenic cardiomyopathy (ACM).
Mar 2, 2023
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The heart disease arrhythmogenic cardiomyopathy can lead to sudden death, particularly affecting young athletes. Researchers at the University of Basel have now genetically modified mice, which develop a similar disease to ...
Nov 2, 2022
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