MeSH tree: A11.284.430.106.279.692.630
Researchers from Queen Mary University of London have uncovered a previously unknown mechanism by which HIV-1 can infect resting immune cells. The discovery challenges a decades-old assumption in HIV biology, and opens new ...
May 6, 2026
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Inside each of your cells lies a nucleus, its master command center. Protected inside each nucleus are your chromosomes, containing all the genetic instructions for making proteins. To keep the body operating smoothly, proteins, ...
Mar 9, 2026
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When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear pore are key players. However, ...
Jan 14, 2026
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In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell's nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, eBIC director at Diamond, ...
Jul 21, 2025
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Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a University of Pittsburgh team ...
Feb 18, 2025
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A group of researchers discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take ...
Oct 9, 2024
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A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center ...
Sep 12, 2024
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Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it—inventing all sorts of tricks.
Jan 25, 2024
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UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
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Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
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