MeSH tree: A11.284.430.214.190.875.190.550
Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center–Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) support the potential of new therapies ...
Mar 5, 2026
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Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break down or get overwhelmed, ...
Jan 22, 2026
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Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.
Jan 16, 2026
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Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far. A new study shows how this Trojan Horse strategy works better by exploiting ...
Nov 25, 2025
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Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough, published in Cell Stem ...
Nov 24, 2025
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Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently uncovered how mitochondria, ...
Oct 25, 2025
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Modern lifestyles and dietary changes have significantly increased the consumption of high-fat foods, contributing to a steep rise in the prevalence of obesity, diabetes, and metabolic disorders. Furthermore, a high-fat diet ...
Sep 17, 2025
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Mayo Clinic researchers have pinpointed how excessive alcohol consumption contributes to fatty liver disease, a condition that affects more than one in three people in the U.S.
Sep 3, 2025
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A team of scientists led by Duke-NUS Medical School has solved a mystery behind a rare and previously undiagnosed disease that affects multiple organs, shedding new light on its cause—and offering fresh hope for treatment.
Aug 29, 2025
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Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal ...
Jul 16, 2025
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