MeSH tree: A11.284.430.214.190.875.190.550
A team of scientists led by Duke-NUS Medical School has solved a mystery behind a rare and previously undiagnosed disease that affects multiple organs, shedding new light on its cause—and offering fresh hope for treatment.
Aug 29, 2025
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Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published in The EMBO Journal shows that the cells deliberately slow the activity of their internal waste disposal ...
Jul 16, 2025
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The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell death, is also necessary ...
May 1, 2025
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Scientists have uncovered more than 20 genes whose mutations cause familial forms of Parkinson's disease. One of these genes is known as VPS13C, and mutations in this gene may contribute to the disease's onset by causing ...
Apr 22, 2025
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Experimental drug NU-9—a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS)—improves neuron health in animal models ...
Apr 8, 2025
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Northwestern Medicine scientists have uncovered new insights into how neurofilaments act like Velcro in neurodegenerative diseases, clogging up the brain and preventing normal function, according to a study published in the ...
Mar 11, 2025
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The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic buildup of the notorious tau protein, which can contribute to Alzheimer's and related diseases.
Mar 5, 2025
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A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism that could be exploited ...
Feb 4, 2025
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Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing digestive enzymes into ...
Jan 2, 2025
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Mitochondria play an essential role in maintaining cellular health. When damaged, they are removed through a recycling process called mitophagy, which is crucial for the function of long-lived cells, especially in the brain. ...
Nov 14, 2024
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