MeSH tree: A11.284.420.460
A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons—and how this can be repaired with simple delivery of energy (ATP). Parkinson's gradually destroys dopamine-producing ...
Mar 2, 2026
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Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that something isn't right.
Scientists have, for the first time, directly visualized and quantified the protein clusters believed to trigger Parkinson's, marking a major advance in the study of the world's fastest-growing neurological disease.
Oct 1, 2025
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Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment—similar to the thin air found at Mount Everest base camp—can protect the brain and restore movement in mice with Parkinson's-like ...
Aug 6, 2025
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A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, new research led by Oregon Health & Science University finds.
Apr 9, 2025
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A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.
Feb 25, 2025
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Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the ...
Feb 18, 2025
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Researchers at Tel Aviv University (TAU) discovered a new factor in the pathology of Parkinson's disease, which in the future may serve as a target for developing new treatments for this terrible ailment, affecting close ...
Nov 12, 2024
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Lewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.
Oct 8, 2024
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Parkinson's disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called α-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies ...
Jul 25, 2024
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