MeSH tree: C16.131.666.507
Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of Ndel1, an enzyme that plays a key role in neuron proliferation, differentiation and migration during embryo development, ...
Oct 24, 2023
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Before SARS-CoV-2 and COVID-19, there was the Zika virus epidemic, lasting from 2015 to 2016. The Zika virus can cause serious birth defects and abnormalities. During the epidemic, one of the most striking results of Zika ...
Sep 21, 2023
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An international team led by a newly appointed Canada Research Chair at the University of Ottawa's Faculty of Medicine has shed light on the underlying mechanisms of a mysterious brain abnormality that occurs during human ...
Sep 14, 2023
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More cases of children born with abnormal brain development may have genetic explanations than previously thought, according to a recent study published in JAMA Neurology.
Aug 17, 2023
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Prenatal exposure to viruses capable of infecting the fetal brain, particularly in the first trimester, can cause a range of developmental defects in the baby. The Zika epidemic in Brazil during 2015–16 posed an extreme case, ...
Aug 9, 2023
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Brain development consists of a sequence of coordinated steps, which are mainly instructed by our genes. During these steps, the proper positioning and functionality of nerve cells in the brain (neurons) are critical—nonfunctional ...
Mar 29, 2023
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Just like pruning a tree helps promote proper growth, the brain uses synaptic pruning to get rid of unnecessary connections between its cells. However, when this normal process, which occurs between early childhood and adulthood, ...
Mar 23, 2023
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203
Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.
Feb 15, 2023
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The outer layer of the human brain (the cerebral cortex), characterized by its distinctive gyri and sulci (those distinctive ridges and furrows), controls cognitive and executive function, from conscious thought to speech ...
Jan 18, 2023
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Northwestern Medicine scientists have identified disease-causing DNA variants in two genes linked to neurodevelopmental deficits including microcephaly in children, according to findings published in Nature Communications.
Dec 15, 2022
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