MeSH tree: C16.320.070
Individuals with sickle cell disease—a chronic illness where misshapen, sticky blood cells clump together, reducing oxygen delivery to organs—are at a higher risk for stroke and resulting cognitive disability. But even in ...
Jan 17, 2025
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The new gene therapies for sickle cell disease—including the gene-editing treatment Casgevy, based on research at Boston Children's Hospital—have been game-changing for the patients who have received them. But Stuart Orkin, ...
Dec 18, 2024
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Though he doesn't remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of the hospital with pain episodes, not knowing why. As he got older, he learned he had ...
Dec 7, 2024
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Who doesn't love to cozy up with a hot water bottle during the colder months? Hot water bottles are a quick, easy and cost effective way of staying warm in winter—but they can also cause serious injury.
Dec 3, 2024
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Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene Therapy. To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, ...
Nov 19, 2024
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Blood stem cells develop through different stages to become fully mature red blood cells. This fundamental biologic process is defined by a series of complex metabolic processes, which are often dysregulated in blood disorders ...
Nov 15, 2024
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Many individuals with sickle cell anemia undergoing controlled ovarian hyperstimulation (COH) with oocyte cryopreservation (OC) have complications, according to a study scheduled for presentation at the annual meeting of ...
Nov 14, 2024
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RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying genetic disease.
A little-noticed change to South Africa's national health research guidelines, published in May of this year, has put the country on an ethical precipice. The newly added language appears to position the country as the first ...
Oct 26, 2024
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Early results from a study of newborn screening methods show that DNA analysis picks up many more preventable or treatable serious health conditions than standard newborn screening and is favored by most parents who are offered ...
Oct 24, 2024
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