MeSH tree: C06.130.120.200
Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA). This cancer is ...
Jun 20, 2024
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48
A clinical trial led by Birmingham researchers investigated targeting a molecule causing liver inflammation and fibrosis to treat patients with Primary sclerosing cholangitis (PSC)—a debilitating liver disease for which there ...
May 14, 2024
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35
A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured. However, a liver can produce too much collagen when an excess ...
Apr 26, 2024
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85
Certain demographic, clinical, and genetic factors heighten the risk for extraintestinal manifestations (EIMs) with inflammatory bowel disease (IBD), according to a study published online March 13 in Gastroenterology.
Apr 17, 2024
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Primary sclerosing cholangitis (PSC) is a severe and chronic liver disease. It affects men more than women, and most people who are diagnosed with PSC are between 30 and 40 years old.
Feb 16, 2024
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70
Research from the Gupta Lab provides important insights into the extrahepatic bile ducts. These bile ducts outside of the liver are a critical but poorly understood component of the human digestive system. The study, led ...
Dec 11, 2023
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The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called hepatocytes. When the ...
Sep 6, 2023
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25
A mechanism underlying several liver diseases involves bile produced in the liver that cannot be secreted into the intestine as intended. This leads to a backlog of bile, which can damage the liver tissue.
Jul 3, 2023
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Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, ...
May 24, 2023
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48
DEAR MAYO CLINIC: My husband is 45 and has lived with irritable bowel syndrome for many years. He was recently diagnosed with primary sclerosing cholangitis. Are these two conditions related? We were told a liver transplant ...
Jul 14, 2022
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403
