MeSH tree: D08.811.277.656.262.500.126
A study led by Daniel Jane-Wit, MD, Ph.D., a Yale School of Medicine associate professor of medicine (cardiology) and of immunobiology, could revolutionize our understanding of immune signaling. The study, published May 24 ...
Jun 14, 2023
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Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to ...
Jun 1, 2023
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In animals, a process of programmed cell death called apoptosis ensures cells die when they should. An opposing force, governed by inhibitor of apoptosis proteins (IAPs), guards against excessive cell death. Together these ...
Feb 9, 2023
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Researchers have used fruit flies to decipher an unexplained connection between Alzheimer's disease and a genetic variation, revealing that it causes neurons to die.
Jan 9, 2023
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A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the ...
Dec 22, 2022
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Neurodegenerative disorders such as Alzheimer's and Parkinson's disease are associated with atypical proteins that form tangles in the brain, killing neurons. Neurobiologists at EPFL have now identified some key mechanisms ...
Aug 29, 2022
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Researchers from Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine of The University of Hong Kong (HKUMed) revealed insights into the mechanism of how coronaviruses including SARS-CoV-2, ...
Aug 4, 2022
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A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.
Jul 28, 2022
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