Rapid test could help pinpoint IBD diagnosis, study suggests
A test that rapidly detects signs of inflammatory bowel disease (IBD) in stool samples could improve future diagnosis and monitoring of the condition, a study suggests.
Jan 13, 2026
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Enzymes: News and Research on Granzymes
MeSH tree: D08.811.277.656.959.350.397
Researchers find immune pathway in joint tissue involved in early rheumatoid arthritis
A new study by scientists at the University of Colorado Anschutz Medical Campus reveals that joint tissue from patients with early-stage rheumatoid arthritis often have high levels of a protein called granzyme used by the ...
Jul 2, 2025
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Synthetic mRNA therapy: Study introduces weapon against metastatic cancer without harmful side effects
Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple organs, conventional treatments like surgery, radiation, and chemotherapy become less effective. ...
Mar 17, 2025
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Novel PET imaging tool identifies early signs of inflammatory bowel disease and predicts response to treatment
A newly developed imaging method, granzyme B PET, can non-invasively detect inflammatory bowel disease (IBD) and provide a real-time picture of active inflammation in the tissue, according to new research published in the ...
Jul 25, 2024
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Study finds immunotherapy combination before surgery improves outcomes for patients with pancreatic cancer
A pilot study led by UCLA Health Jonsson Comprehensive Cancer Center investigators suggests that for people with borderline resectable pancreatic cancer, administrating an immunotherapy drug in combination with chemotherapy ...
Apr 5, 2024
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Immune cells lose 'killer instinct' in cancerous tumors, but functionality can be re-awakened
Some immune cells in our bodies see their "killer instinct" restricted after entering solid tumors, according to new research.
Feb 2, 2024
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Memory CD8 T cells promote pathogenic plaque buildup of the arteries in aged mice: Study
Aging is known to be a risk factor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells, a type of immune cell, ...
Dec 13, 2023
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Unveiling a novel immune response in the intestinal epithelium
Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism ...
Oct 31, 2023
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Cytotoxic CD4+ T-cells correlated to severe and fatal COVID-19 outcomes
Research led by the University of Sydney, Australia, has uncovered an important driver of critical SARS-CoV-2 infections. In their paper, "A unique cytotoxic CD4+ T cell-signature defines critical COVID-19," published in ...
Discovery in T-cell research could lead to improved treatment of solid tumors
A local study led by the Agency for Science, Technology and Research (A*STAR) discovered that by inhibiting the function of two proteins, G9a and GLP, during the cell therapy production process, immune cells could become ...
Jul 10, 2023
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