MeSH tree: D08.811.682.608
For decades, physicians and scientists thought metformin, the leading type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production. But a new Northwestern University study ...
May 8, 2026
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172
Alain Chariot's team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, ...
Apr 2, 2026
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5
Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks. Now, researchers from Japan have ...
Mar 30, 2026
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Oxidative stress is a direct consequence of an excess in the body of so-called free radicals—reactive, unstable molecules that contain oxygen. Free radicals are normal metabolic by-products and also help to relay signals ...
Feb 10, 2026
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Changes in how brain cells generate energy may drive the development of Alzheimer's disease and influence how patients respond to therapy, according to a new study from Mayo Clinic researchers. The findings, published in ...
Aug 7, 2025
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Millions of people take metformin, a type 2 diabetes medication that lowers blood sugar. The "wonder drug" has also been shown to slow cancer growth, improve COVID outcomes and reduce inflammation. But until now, scientists ...
Dec 18, 2024
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Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers ...
Sep 20, 2024
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A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis ...
Jan 2, 2024
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Researchers led by the ESRF, the European Synchrotron, have found that amyloid oligomers play a role in speeding up mitochondrial energetics during the early stages of Alzheimer's, in contrast to what has been previously ...
Dec 14, 2023
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A new research paper was published in Aging, titled, "Contribution of membrane raft redox signaling to visfatin-induced inflammasome activation and podocyte injury."
Dec 5, 2023
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