MeSH tree: G05.308.203.374
Most people who have heard of clustered regularly interspaced short palindromic repeats (more commonly known as CRISPR) associate it with gene editing—the precise molecular scissors that allow scientists to cut and rewrite ...
Mar 29, 2026
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Dilated cardiomyopathy (DCM), a leading cause of heart failure, is twice as common in Black individuals as in white individuals. This excess risk is not fully explained by known risk factors such as high blood pressure or ...
Nov 2, 2025
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Immunotherapy employs patients' own immune systems to fight cancer, and it has shown itself to be an effective treatment in many cases. However, some cancers, like triple-negative breast cancer (TNBC), show resistance to ...
University of North Carolina Lineberger Comprehensive Cancer Center researchers have developed a "two-in-one" molecule that can simultaneously turn off two notoriously difficult-to-target cancer-related genes, KRAS and MYC, ...
Aug 4, 2025
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Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Jun 25, 2025
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A simple, freely available analysis tool and hardware for analyzing fruit flies allows opportunities for researchers in low-income settings or out in the field to screen for genes and nerve circuits underlying complex social ...
Mar 25, 2025
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Since its discovery in 1998 and winning the Nobel Prize in 2006, ribonucleic acid (RNA) interference has become an invaluable tool for drugmakers to silence disease-causing genes. Nearly three decades later, drug makers have ...
Nov 13, 2024
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In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
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About one-third of adults have high blood pressure. Two-thirds of these have uncontrolled high blood pressure.
Jul 15, 2024
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Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.
Jun 13, 2024
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