Genetic Phenomena: News and Research on Genes, BRCA1

MeSH tree: G05.360.340.024.340.415.400.100

What is a 'cancer gene'? How genetic mutations lead to cancer

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, change what they do and ...

Cell nucleus shape may influence cancer treatment success

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The results may also explain why ...

Why preventive mastectomy isn't offered to everyone at risk

When Jesse J, Christina Applegate and Katie Thurston spoke openly about their mastectomies, their candor did more than share private struggles. It highlighted a procedure that, while often life saving, is unevenly available ...

How breast cancer drugs exploit genomic fractures in tumors

Studying families with multiple members who had breast cancer first led to the discovery of mutations in BRCA genes. Doctors have since learned that these mutations increase the risk of developing multiple tumor types, including ...

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