Target discovered for the treatment of pancreatic cancer
A team at the Institute of Biochemistry at Kiel University has found a way to inhibit the function of the tumor-causing protein MYC. This can be used to develop new drugs.
Jul 4, 2024
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Genetic Phenomena: News and Research on Genes, myc
MeSH tree: G05.360.340.024.340.375.500.791.420
Researchers detail molecular pathway that impacts pancreatic cancer progression and treatment response
Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or "oncogene," and how its activities ...
Jun 6, 2024
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The inhibitory effect of miR-377 on prostate cancer cells
A new research paper titled "Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4" has been ...
May 21, 2024
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New research sheds light on the weakening immune response observed in older adults
A fully functioning immune system is essential to help the body maintain good health, and macrophages play a critical role in maintaining robust immune responses against infections.
Apr 26, 2024
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Liver cancer: Molecular signaling pathway of tumor development decoded
As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain limited, the incidence is ...
Apr 23, 2024
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Investigational therapeutic shows promise in preclinical pancreatic cancer model
A new type of investigational therapeutic in development for pancreatic cancer has shown unprecedented tumor-fighting abilities in preclinical models of the disease, suggesting it has the potential to offer novel treatment ...
Apr 8, 2024
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Protein discovery sparks treatment hope for aggressive cancer
Researchers have found a new way to potentially treat one of the most common forms of acute lymphoblastic leukemia.
Mar 14, 2024
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RNA-based therapy shows promise against aggressive childhood brain tumors in mice
Targeting a non-encoding stretch of RNA may help shrink tumors caused by an aggressive type of brain cancer in children, according to new research in mice reported March 8 in Cell Reports by Johns Hopkins Kimmel Cancer Center ...
Mar 13, 2024
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Study offers new insights into earliest stages of brain tumor development
Scientists working to better understand and find a cure for brain tumors have made progress in identifying initial events in cells that can lead to tumor growth.
Mar 12, 2024
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New insights into the growth and spread of cancer cells
Cancer cells are characterized by their aggressiveness: they grow rapidly and spread to other parts of the body. To enable this, numerous mechanisms come into play, and one of them involves a protein called MYC, which activates ...
Mar 7, 2024
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