MeSH tree: C15.378.050.141.150.150
The new gene therapies for sickle cell disease—including the gene-editing treatment Casgevy, based on research at Boston Children's Hospital—have been game-changing for the patients who have received them. But Stuart Orkin, ...
Dec 18, 2024
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Though he doesn't remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of the hospital with pain episodes, not knowing why. As he got older, he learned he had ...
Dec 7, 2024
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Who doesn't love to cozy up with a hot water bottle during the colder months? Hot water bottles are a quick, easy and cost effective way of staying warm in winter—but they can also cause serious injury.
Dec 3, 2024
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Researchers described a promising new approach for using gene therapy to treat sickle cell disease in the journal Human Gene Therapy. To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, ...
Nov 19, 2024
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Blood stem cells develop through different stages to become fully mature red blood cells. This fundamental biologic process is defined by a series of complex metabolic processes, which are often dysregulated in blood disorders ...
Nov 15, 2024
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Many individuals with sickle cell anemia undergoing controlled ovarian hyperstimulation (COH) with oocyte cryopreservation (OC) have complications, according to a study scheduled for presentation at the annual meeting of ...
Nov 14, 2024
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A little-noticed change to South Africa's national health research guidelines, published in May of this year, has put the country on an ethical precipice. The newly added language appears to position the country as the first ...
Oct 26, 2024
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Gene-editing therapies—techniques that modify DNA to treat or prevent disease—have the potential to transform the field of drug development. By making precise edits to the genome, problematic genes could be modified or eliminated, ...
Oct 21, 2024
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The question of what causes complex neurological diseases such as Alzheimer's or multiple sclerosis continues to confound scientists and doctors, with the unknowns standing in the way of early diagnoses and effective treatments.
Oct 17, 2024
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A series of community made videos have proven to be an effective way to encourage Black people to donate blood, with research showing this arts-based approach could help to boost much needed blood supplies.
Oct 14, 2024
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