'Never did I imagine that I would have to ration chemotherapy'
Nationwide shortages of two dozen chemotherapy drugs are leading to rationing and delays in treatment for cancer patients, local and national authorities say.
May 22, 2023
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Heterocyclic Compounds: News and Research on Methotrexate
MeSH tree: D03.633.100.733.631.192.500
Researchers announce findings from landmark clinical trial for pediatric Crohn's disease
Crohn's disease is a lifelong inflammatory bowel disease (IBD) that is characterized by swelling in the lining of the digestive tract, causing severe diarrhea, abdominal pain, and rectal bleeding. For pediatric patients, ...
Apr 4, 2023
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Hair regrowth seen in alopecia with methotrexate + prednisone
For patients with recalcitrant alopecia areata totalis or universalis, methotrexate combined with prednisone yields complete hair regrowth in about 31 percent of patients, according to a study published online March 8 in ...
Mar 15, 2023
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Gene essential to making DNA appears to be a good target in minimizing pulmonary hypertension
The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to ...
Mar 14, 2023
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Abatacept therapy offers promising results for treating juvenile dermatomyositis
Juvenile dermatomyositis, a rare but often severe and chronic systemic autoimmune disease, includes a large number of patients who are treatment resistant, requiring long term immunosuppressive therapy. A small open-label ...
Mar 8, 2023
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Study finds use of methotrexate is associated with an increased risk of skin cancer
The immunosuppressive drug methotrexate (MTX) can be linked to an elevated risk of three types of skin cancer, a new study by University of Gothenburg researchers shows. Patients receiving the drug include those with moderate ...
Feb 7, 2023
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Nearly 10 percent of psoriasis patients have high risk for liver fibrosis
About 10 percent of patients with psoriasis have a high risk for advanced liver fibrosis, according to a systematic review and meta-analysis published online Dec. 15 in Frontiers in Medicine.
Jan 4, 2023
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Updated rheumatoid arthritis treatment recommendations
Since their first publication in 2010, the EULAR recommendations for the use of disease-modifying anti-rheumatic treatments (DMARDs) in people with rheumatoid arthritis (RA) have become a most important publication in the ...
Nov 11, 2022
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Revised ACR/EULAR rheumatoid arthritis remission criteria released
The first provisional criteria for defining remission in rheumatoid arthritis (RA) were drawn up by EULAR and the ACR in 2011. Two types of remission definition were agreed on.
Nov 9, 2022
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Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold
New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that discontinuing methotrexate for one week after seasonal influenza vaccination provided the same seroprotection ...
Nov 8, 2022
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