Heterocyclic Compounds: News and Research on Purines

MeSH tree: D03.633.100.759

How do GLP-1 agonists affect gene expression?

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health. ...

Why is gout on the rise?

A condition once called the "disease of kings" is affecting even the general population. Rates of gout, a type of inflammatory arthritis that causes severe, sudden stabbing pain in the big toe, have increased by more than ...

Vitamin B3 therapy offers hope for fatal childhood disease

Scientists at Gladstone Institutes have flipped the traditional approach to finding potential treatments for deadly diseases. Instead of starting with a disease and hunting for a cure, they began with vitamins and systematically ...

Stimulating mitochondria to boost long-term memory

An international team led by Jaime de Juan-Sanz at the Paris Brain Institute has shown that slightly increasing the metabolic capacity of neurons can enhance long-term memory in both fruit flies and mice. The study, published ...

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