What is gout—and what are the early warning signs to look out for
New research indicates that a drug commonly prescribed for gout may also lower the risk of heart attack and stroke when taken at an appropriate dose.
Feb 9, 2026
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Heterocyclic Compounds: News and Research on Allopurinol
MeSH tree: D03.633.100.759.160
Use of glucose-lowering SGLT2i drugs may help patients with gout and diabetes take fewer medications
Gout, a type of inflammatory arthritis caused by a buildup of uric acid (urate) in the body, affects 5.1% of U.S. adults (over 12 million), including 10% of those aged 65 or older. Urate is produced by the body when breaking ...
Feb 3, 2026
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Gout medication may reduce the risk of heart attack and stroke
A new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout.
Jan 26, 2026
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New genetic marker could improve prediction of severe gout drug reactions in US patients
A newly identified genetic marker may significantly improve the ability to predict life-threatening reactions to the gout medication allopurinol in U.S. patients.
Oct 29, 2025
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Allopurinol designated as the first orphan drug for Marfan syndrome treatment
The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which has no cure to date. This disease causes an aortic aneurysm ...
May 19, 2025
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Study finds genetics, not lifestyle, is a major cause of gout
A major international study has found that gout is a chronic illness in which genetics is a major cause, rather than the lifestyle choices of the sufferer.
Oct 15, 2024
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Allopurinol may cut risk for neurodegenerative diseases
Xanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 in PLOS ONE.
May 19, 2023
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A sharp increase in the price of gout drug colchicine led to lower use and poorer disease control, research suggests
Due to a policy decision in 2010 by the U.S. Food and Drug Administration (FDA), the price of a prescription for the therapeutic gout drug colchicine increased nearly 16-fold from $11.25 in 2009 to $190.49 in 2011. Out-of-pocket ...
May 8, 2023
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Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients
The gout medicine allopurinol has failed to reduce the primary endpoint of nonfatal myocardial infarction, nonfatal stroke or cardiovascular death in patients with ischemic heart disease, according to late breaking research ...
Aug 29, 2022
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