Aging reduces CAR-T cell effectiveness by impairing metabolism, study shows
As people age, their immune systems become less efficient, posing a challenge for cancer therapies that rely on harnessing immune cells.
May 20, 2025
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Heterocyclic Compounds: News and Research on NAD
MeSH tree: D03.633.100.759.646.138.694
Time to trash your supplements? Low levels of NAD⁺ may not drive aging
In his recent Netflix documentary, Don't Die: The Man Who Wants to Live Forever, tech millionaire Bryan Johnson reveals that he includes NAD precursors in his expansive supplement routine, totaling more than 50 pills a day.
May 1, 2025
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Most in-depth simulation of brain metabolism yet reveals new targets for future dementia treatments
A new open-source model of brain metabolism—the most complex ever generated—has shown how altering key chemicals could restore aged cells to their youthful activity and resilience.
Mar 25, 2025
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Topical steroid withdrawal diagnostic criteria defined by researchers
Researchers at the National Institutes of Health (NIH) have determined that dermatitis resulting from topical steroid withdrawal (TSW) is distinct from eczema and is caused by an excess of an essential chemical compound in ...
Mar 14, 2025
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When you get hurt matters: Circadian rhythms shown to play a role in muscle repair
The body's internal clock doesn't just dictate when we sleep—it also determines how quickly our muscles heal. A new Northwestern Medicine study in mice, published today in Science Advances, suggests that muscle injuries heal ...
Mar 5, 2025
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Molecular mechanism of ergothioneine decoded: Mushroom compound may lead to prolonged health
Many people wish not only to live as long as possible, but above all to do so without any health restrictions. However, with increasing age, the risk of age-related diseases such as Alzheimer's or sarcopenia (loss of muscle ...
Jan 20, 2025
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Newly discovered mechanism reveals NAD's role in aging and disease
UiB researchers are behind a new discovery that tells us how associated neurodegenerative diseases might develop. At the center of this discovery stands a molecule called NAD, or nicotinamide adenine dinucleotide. The results ...
Dec 23, 2024
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Promising results for COPD treatment: Researchers find form of vitamin B3 reduces lung inflammation
We live longer and longer, and as we age, a lot of us develop a series of health issues and chronic diseases, including chronic obstructive pulmonary disease (COPD), which is found in around 600 million individuals globally. ...
Nov 20, 2024
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Scientists find potential therapy for fatty liver disease
Metabolic dysfunction-associated steatotic liver disease (MASLD)—previously known as "non-alcoholic fatty liver disease"—affects about 25% of the global population. Its severe form, metabolic dysfunction-associated steatohepatitis ...
Oct 9, 2024
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New approach enables a closer look at microglial organelles
Microglia are the immune system's front-line enforcers in the brain. They are cells that patrol the brain and destroy anything harmful that they encounter, from invading bacteria to cellular debris. They also remove plaques ...
Aug 16, 2024
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