MeSH tree: D06.472.334.851.437.500.500
Researchers at Baylor College of Medicine and collaborating institutions have developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary cause of death for most ...
Apr 28, 2026
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The U.S. Food and Drug Administration has approved Eli Lilly's Inluriyo (imlunestrant), an oral estrogen receptor antagonist, for the treatment of adults with estrogen receptor-positive, human epidermal growth factor receptor ...
Oct 1, 2025
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Institut Curie researchers have identified a sex-specific molecular pathway connecting E-cadherin loss, estrogen receptor-α (ERα), and GRPR, contributing significantly to increased melanoma metastasis in women.
For patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer, the oral proteolysis-targeting chimera ER degrader, vepdegestrant, leads to significantly ...
Jun 2, 2025
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Mutations in the PIK3CA gene are a key driver of breast cancer and are present in 35–40% of hormone receptor–positive breast cancers. A recently completed phase 3 clinical trial, conducted by researchers at Mass General Brigham ...
Jun 2, 2025
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A new drug that helps slow the spread of an incurable type of breast cancer has been approved for use in Britain's state-run National Health Service, officials said on Friday.
Apr 11, 2025
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By age 75, a noteworthy 50% of men develop an inguinal (groin) hernia—a bulge that results from soft tissue pushing through a weak spot in the abdominal muscles. Although common, the cause of these hernias is unknown, and ...
Feb 5, 2025
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A powerful, three-drug therapy for aggressive advanced breast cancer doubles the length of time before the cancer progresses, compared with a drug combination currently available on the NHS, new research has shown.
Oct 31, 2024
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The U.S. Food and Drug Administration has approved Itovebi (inavolisib), in combination with palbociclib (Ibrance) and fulvestrant, for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, ...
Oct 16, 2024
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Researchers have identified why some advanced estrogen receptor (ER) positive breast cancers become resistant to hormone therapy, and have identified drugs currently in development that could keep disease stable for longer ...
Feb 7, 2024
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