Study in mice reveals a link between maternal stress during pregnancy and childhood eczema
Maternal stress during pregnancy may be partly to blame for childhood eczema, according to a study on mice published in the journal Nature.
Immune System: News and Research on Mast Cells
MeSH tree: A15.382.652
Mouse study uncovers mast cells' role as gatekeepers against pathogens
The itching, redness and swelling of an allergic reaction are caused by mast cells—the vigilant first responders of the immune system that spring into action with histamine-filled granules in response to a perceived threat.
Jul 31, 2025
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High levels of antihistamine drugs can reduce fitness gains, study finds
For some, the word "histamine" might evoke thoughts of seasonal allergies: runny noses, scratchy throats and itchy eyes. But the molecule also influences exercise performance.
Jun 18, 2025
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Bioactive compound blocks key immune receptor to ease hard-to-treat allergic reactions
Irritable bowel syndrome, chronic itching, asthma and migraine are in many cases hard-to-treat conditions. They have in common that they are triggered by an excessive immune response—which in severe cases can be life-threatening.
Apr 24, 2025
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Psychological stress may cause food-induced symptoms in IBS
Scientists have discovered that psychological stress can induce immune responses to food that can cause symptoms when that food is eaten again, findings that demonstrate the potential role of stress in symptoms of irritable ...
Mar 17, 2025
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New study explains why you shouldn't scratch an itchy rash
New research published in the journal Science uncovers how scratching aggravates inflammation and swelling in a mouse model of a type of eczema called allergic contact dermatitis.
Jan 30, 2025
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A new way to treat inflammatory skin conditions: Experimental compound targets mast cells
A new approach to treat rosacea and other inflammatory skin conditions could be on the horizon, according to a University of Pittsburgh study published in Science Translational Medicine.
Dec 11, 2024
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Pathway behind stress-triggered migraines discovered
Migraines are more than just bad headaches; they stem from a genetic neurological disease that causes suffering for one in seven people. Those who experience migraines can have a myriad of debilitating symptoms, including ...
Nov 21, 2024
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Study deciphers pathological mechanisms of spermatogenic impairment in cryptorchidism
Cryptorchidism is a common congenital abnormality in male newborns. Studies have found that cryptorchidism is associated with a high prevalence of male infertility, with nearly 10% of men with fertility problems having a ...
Sep 9, 2024
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Mechanisms of postoperative pain reveal a path for localized and targeted therapy
An international research group led by MedUni Vienna and IMBA—Institute of Molecular Biotechnology, Vienna, has made significant progress in understanding the mechanisms that influence the sensation of pain after surgery.
Aug 26, 2024
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