MeSH tree: E05.196.309.742.225
Drug discovery can be a frustrating process of trial and error. Scientists using fragment-based drug discovery link fragments of different molecules together to create a more potent drug but may not know whether a compound ...
Feb 28, 2024
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As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.
Feb 2, 2024
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What if we could engineer our immune system to make the human body better at fighting cancer? Professor Roy Mariuzza is part of a major research effort aimed at doing just that. An expert in the structural biology of immune ...
Oct 12, 2023
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An international team of scientists has developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system.
Sep 18, 2023
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A collaboration between the Márquez group at EMBL Grenoble and Italian researchers from the European Biomedical Research Institute of Salerno (EBRIS) has led to the development and characterization of a novel small molecule ...
Jul 7, 2023
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In a new study, researchers examined how a country's number of published 3D protein structures for coronaviruses, including the one responsible for COVID-19, correlated with its economic output and population. The findings ...
Mar 27, 2023
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In 2019 Dr. Stephen Withers and colleagues at the University of British Columbia identified a series of enzymes that can be used to modify the chemical structure of a sugar antigen on the surface of blood cells, thereby converting ...
Jan 24, 2023
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Food allergies are caused by IgE antibodies that are generated by the immune system and bind to allergens such as peanuts, triggering a reaction that in extreme cases can be potentially life-threatening.
Jan 19, 2023
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Proteins do not have a single shape, but are more like dynamic robots. But—how do they actually move? And what does this tell us about their function? Laura Orellana describes the movement of proteins using computer simulations—and ...
Jan 16, 2023
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Structural details of an attractive drug target in coronaviruses that could be used against SARS-CoV-2 and in future pandemics have been published today in eLife.
Nov 22, 2022
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