MeSH tree: E05.393.760.700.825.500
A dual-threshold model for measuring the pancreatic tumor marker serum carbohydrate antigen 19-9 (CA19-9) identified patients with pancreatic cancer who had high-risk disease despite having low CA19-9 levels because of a ...
May 21, 2026
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Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare diseases.
Apr 15, 2026
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Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published ...
Mar 31, 2026
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People often remark that allergies run in their family, but the genetic causes have remained unclear. Previous food allergy genetic research has relied upon broad but surface-level methods called genome-wide association studies.
Feb 20, 2026
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Cells from cancerous tumors can spread, or metastasize, throughout the body. Researchers have long sought to understand what determines where those cells will go and thrive in order to more effectively treat the cancer and ...
Feb 9, 2026
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The National Institutes of Health established the Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium in 2021 with the goal of finding molecular diagnoses for individuals with rare diseases who ...
Nov 21, 2025
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Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women—but until now, they have been underrepresented in genomic studies aimed at identifying the genetic ...
Aug 26, 2025
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Researchers have demonstrated a specific type of genetic variation in obsessive-compulsive disorder (OCD) for the first time using advanced DNA sequencing technology. The findings support previous studies by the same group ...
Jun 18, 2025
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T-follicular helper (TFH) lymphoma is a blood cancer subgroup that continues to demonstrate a generally poor prognosis, with no standard treatment established to date. Although specific genetic mutations are frequently observed ...
Jun 10, 2025
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Exome sequencing (ES) is commonly used to diagnose Mendelian disorders, which occur when pathogenic variant(s) in a gene are either inherited from one or both parents or are de novo. Examples of such disorders include cystic ...
May 5, 2025
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