MeSH tree: D05.500.562
Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers ...
Sep 20, 2024
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Drosophila—commonly known as fruit flies—are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy. However, a choke point in evaluating fruit fly hearts is the need for human intervention ...
Jul 3, 2024
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Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts. A protein's structure is critical to its function. Malformed proteins not only fail to carry out their ...
Apr 30, 2024
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The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but, Johns Hopkins Medicine ...
Apr 12, 2024
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Virginia Tech researchers have discovered a new function for a common protein in the brain—a development that sheds new light on the mysteries of the mind and holds promising implications for the treatment of memory loss ...
Jan 25, 2024
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A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis ...
Jan 2, 2024
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Researchers led by the ESRF, the European Synchrotron, have found that amyloid oligomers play a role in speeding up mitochondrial energetics during the early stages of Alzheimer's, in contrast to what has been previously ...
Dec 14, 2023
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Smart users of social media protect themselves by deleting suspicious "friend requests" that might serve as a gateway to harmful content. Similarly, our immune system uses its own judgment to identify cellular "profiles" ...
Sep 20, 2023
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Mopping up free radicals with antioxidants was the rage in the 1970s; people were taking large, sometimes massive doses of various general antioxidants, including vitamins and minerals, to try to remove harmful byproducts ...
Jul 10, 2023
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Scientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein clearance within the brain. However, a new study published in Science has revealed that its essential ...
May 25, 2023
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