MeSH tree: C04.557.450.590.550
Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene expression. While progress ...
Mar 18, 2026
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Researchers at Children's Hospital Los Angeles have discovered a key difference between the two main types of rhabdomyosarcoma—paving the way for more targeted treatments.
Jul 23, 2025
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14
An artificial intelligence (AI)-based model accurately classified pediatric sarcomas using digital pathology images alone, according to results presented at the American Association for Cancer Research (AACR) Annual Meeting, ...
Apr 29, 2025
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University of Queensland research using natural killer cells may lead to the first new treatment for a devastating childhood cancer in 40 years. Associate Professor Fernando Guimaraes, a Principal Research Fellow from UQ's ...
Feb 11, 2025
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Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although ...
Jan 17, 2025
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32
Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...
Sep 26, 2024
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Germline cancer-predisposition variants (CPVs) can be helpful in predicting risk in some pediatric cancers. However, CPV risk association in children with rhabdomyosarcoma has not been well studied. A new report led by researchers ...
Mar 28, 2024
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Pediatric rhabdomyosarcoma is a type of cancerous tumor that arises in the soft tissue, such as muscles, though the origin of one of the most aggressive subtypes is unclear.
Nov 15, 2023
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For six years, Professor Christopher Vakoc's lab at Cold Spring Harbor Laboratory has been on a mission to transform sarcoma cells into regularly functioning tissue cells. Sarcomas are cancers that form in connective tissues ...
Aug 28, 2023
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Rhabdomyosarcoma, a malignant tumor, is one of the most common soft tissue tumors occurring during childhood. The tumors are associated with skeletal muscle and can emerge anywhere in the body. Consequently, the clinical ...
Jul 26, 2023
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